Transcription Factor Collection (#2)

Pho4 transcription factor bound to DNA. Molecular model showing phosphate system positive regulatory protein (Pho4) (pink and green) bound to a strand of DNA (deoxyribonucleic acid)

TATA box-binding protein complex C017 / 7087
TATA box-binding protein complex. Molecular model showing a TATA box-binding protein (TBP, green) complexed with a strand of DNA (deoxyribonucleic acid, yellow) and transcription factor IIB

Transcription factor bound to DNA C014 / 0868
Transcription factor bound to DNA. Molecular model showing a MATa1/MATalpha2 homeodomain heterodimer (green and pink) in complex with a strand of DNA (deoxyribonucleic acid, orange and blue)

TATA box-binding protein complex C014 / 0879
TATA box-binding protein complex. Molecular model showing a TATA box-binding protein (TBP, lilac) complexed with a strand of DNA (deoxyribonucleic acid, green and red)

Transcription factor complexed with DNA C014 / 0869
Transcription factor complexed with DNA. Computer model showing sterol regulatory element binding transcription factor 1 (SREBF1, horizontal) bound to a section of DNA (deoxyribonucleic acid)

Transcription factor complexed with DNA C014 / 0870
Transcription factor complexed with DNA. Computer model showing a max protein (green) bound to a strand of DNA (deoxyribonucleic acid, pink)

Oestrogen related receptor-DNA complex. Molecular model of human estrogen related receptor-2 (heRR-2, purple) binding to a strand of DNA (deoxyribonucleic acid, red and yellow-green)

Max transcription factor-DNA complex. Molecular model of the Max transcription factor (purple and red) bound to a strand of DNA (deoxyribonucleic acid, light blue and orange)

Bacterial transcription factor molecule C016 / 2061
Bacterial transcription factor. Molecular model of the transcription factor AmrZ from the bacterium Pseudomonas aeruginosa complexed with DNA (deoxyribonucleic acid)

Notch transcription, molecular model
Notch transcription. Molecular model showing a strand of DNA (deoxyribonucleic acid) being acted upon by various proteins and other molecules

Heat shock transcription factor and DNA C015 / 5558
Heat shock transcription factor and DNA. Molecular model of the binding domain region (purple) of a heat shock protein transcription factor bound to DNA (pink, deoxyribonucleic acid)

SMAD4 protein domain bound to DNA C015 / 6552
SMAD4 protein domain bound to DNA, molecular model. This strand of DNA (deoxyribonucleic acid, green and pink) is surrounded by MH1 domains of the SMAD4 (Mothers against decapentaplegic homolog 4)

SMAD4 protein domain bound to DNA C015 / 6551
SMAD4 protein domain bound to DNA, molecular model. This strand of DNA (deoxyribonucleic acid, red and blue) is surrounded by MH1 domains of the SMAD4 (Mothers against decapentaplegic homolog 4)

Androgen receptor, molecular model C015 / 6113
Androgen receptor. Molecular model of the DNA-binding region of an androgen receptor (purple and red) complexed with DNA (deoxyribonucleic acid, blue and orange)

Androgen receptor, molecular model C015 / 6112
Androgen receptor. Molecular model of the DNA-binding region of an androgen receptor (purple and brown) complexed with DNA (deoxyribonucleic acid, turquoise and red)

Tryptophan repressor bound to DNA C015 / 6243
Tryptophan repressor bound to DNA. Molecular model of the tryptophan (trp) repressor (grey and green, and orange and yellow, across bottom) bound to DNA (deoxyribonucleic) molecules (blue and orange)

Tryptophan repressor bound to DNA C015 / 6242
Tryptophan repressor bound to DNA. Molecular model of the tryptophan (trp) repressor (purple and green, and pink and beige, across bottom) bound to DNA (deoxyribonucleic) molecules (blue and orange)

Transcription factor and DNA molecule C015 / 5344
Transcription factor and DNA molecule. Molecular model of glucocorticoid receptor (GR) transcription factor protein (blue and purple) complexed with a molecule of DNA (deoxyribonucleic acid)

Transcription factor and DNA molecule C015 / 5343
Transcription factor and DNA molecule. Molecular model of glucocorticoid receptor (GR) transcription factor protein (yellow and green) complexed with a molecule of DNA (deoxyribonucleic acid)

Human tumour protein p73 C016 / 2830
Human tumour protein p73. Molecular model of the human tumour protein p73, encoded by the TP73 gene. Like the similar p53, is is a transcription factor of a type known as a tumour suppressor gene

Human tumour protein p73 C016 / 2831
Human tumour protein p73. Molecular model of the human tumour protein p73, encoded by the TP73 gene. Like the similar p53, is is a transcription factor of a type known as a tumour suppressor gene

Human tumour protein p63 C016 / 2681
Human tumour protein p63. Molecular model of the tetramerization domain of the human tumour protein p63, encoded by the TP63 gene

Human tumour protein p63 C016 / 2680
Human tumour protein p63. Molecular model of the tetramerization domain of the human tumour protein p63, encoded by the TP63 gene

TATA box-binding protein complex C013 / 8881
TATA box-binding protein complex. Molecular model showing a TATA box-binding protein (TBP) (purple) complexed with a strand of DNA (deoxyribonucleic acid, blue)

Pit-1 transcription factor bound to DNA C013 / 8872
Pit-1 transcription factor bound to DNA. Molecular model showing pituitary-specific positive transcription factor 1 (Pit-1) (purple and yellow) bound to a strand of DNA (deoxyribonucleic acid)

DNA recognition, molecular model
DNA recognition. Computer model showing MyoD transcription factor, from a mouse (mus musculus), bound to DNA. Transcription factors are proteins that bind to specific sequences of DNA

PPAR regulatory molecule. Molecular model of peroxisome proliferator-activated receptor gamma (PPARG, pink) bound to a DNA (deoxyribonucleic acid) molecule (orange and green)

Transcription initiation complex, diagram
Transcription initiation complex. Diagram of the complex formed by the molecules involved in the initiation of transcription

DNA transcription control. Computer model showing a molecule of the FP50 homodimer (green) from NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells)

Interferon regulatory factor molecule
Interferon regulatory factor. Molecular model of interferon regulatory factor 3 (IRF3, blue and white) bound to a DNA (deoxyribonucleic acid) molecule (yellow)

Transcription factor and ribosomal RNA (rRNA). Molecular model showing the 6 zinc fingers of transcription factor IIIA (purple) bound to RNA (ribonucleic acid)

Transription activation of IFN-beta gene. Computer model showing the molecular structure of an enhanceosome (dark green, purple, blue and red) containing the transcription factors IRF-3

Transcription factor complexed with DNA. Computer model showing sterol regulatory element binding transcription factor 1 (SREBF1, purple and pink) bound to a section of DNA (deoxyribonucleic acid)

Transcription factor-DNA, molecular model. Strand of DNA (deoxyribonucleic acid, yellow) being acted on by a transcription factor protein (red and green)

Testosterone bound to receptor, artwork
Testosterone bound to receptor. Molecular model of a molecule of the male sex hormone testosterone (ball-and-stick primary structure) bound to a human androgen receptor (secondary structure)

THG anabolic steroid and receptor
THG bound to receptor. Molecular model of a molecule of the anabolic steroid drug tetrahydrogestrinone (THG, ball-and-stick primary structure) bound to a human androgen receptor (secondary structure)

GAGA transcription factor molecule. Molecular model showing the primary (rods) and secondary (helices) structure of GAGA factor (green and blue)

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A transcription factor is a crucial player in the intricate process of gene expression. One such example is the MyoD muscle protein-DNA complex, which plays a pivotal role in regulating muscle development and differentiation. Another important transcription factor complex is the TATA box-binding protein (TBP) complex C017 / 7082. This specific complex binds to the TATA box sequence on DNA, initiating transcription by recruiting other factors necessary for RNA synthesis. In addition to its involvement in gene regulation, the TBP complex C017 / 7088 also interacts with various other complexes like C017 / 7084 and C014 / 0867. These interactions further enhance its ability to initiate transcription at specific sites on DNA. Furthermore, another significant interaction involves a transcription factor bound to ribosomal RNA, highlighting its role in controlling protein synthesis within cells. This demonstrates how these factors are not limited to regulating gene expression alone but also have an impact on essential cellular processes. The Pho4 transcription factor bound to DNA (C014 / 0861) showcases yet another fascinating aspect of these proteins' functionality. By binding specifically to certain regions of DNA, this particular factor regulates phosphate metabolism genes, ensuring proper nutrient utilization within cells.