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Anaesthetic inhibiting an ion channel C015 / 6722

Anaesthetic inhibiting an ion channel C015  /  6722


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Anaesthetic inhibiting an ion channel C015 / 6722

Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres) bound to a pentameric ligand-gated ion channel (pLGIC, blue ribbons). Propofol is used for inducing and maintaining general anaesthesia. pLGICs are targeted by general anaesthetics such as propofol which bind to the extracellular interface between the channels five monomers (subunits) and inhibit its action

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9214579

© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Anaesthesiology Anaesthetic Analgesia Anesthesia Anesthetic Binding Bound Cell Biology Channel Complex Complexed Cytological Cytology Drug Electron Density General Anaesthesia Inhibiting Inhibition Interacting Interaction Ion Channel Lgic Lgics Ligand Gated Ion Channel Molecules Nmda Receptor Antagonist Pentameric Ligand Gated Ion Channel Pharmacological Pharmacology Plgic Plgics Proteins Proteomics Quaternary Structure Receptor Receptors Ribbon Structure Secondary Structure System Biochemical Biochemistry Cutouts Molecular Model Molecular Structure Protein


EDITORS COMMENTS
This print showcases the intricate structure of propofol anaesthetic drug molecules bound to a pentameric ligand-gated ion channel (pLGIC). The computer-generated model beautifully illustrates how propofol, a commonly used general anaesthetic, interacts with the ion channel to induce and maintain anesthesia. The image features propofol molecules represented as spheres, elegantly attached to the blue ribbons that depict the pLGIC. These channels are specifically targeted by general anesthetics like propofol, which bind to their extracellular interface between five monomers or subunits, ultimately inhibiting their action. Set against a clean white background, this artwork highlights the complex biochemical interaction between drugs and proteins within our body's systems. The molecular model provides valuable insights into pharmacology and pharmacological mechanisms associated with anesthesia. With its detailed depiction of protein structures and molecular arrangements, this image is not only visually striking but also serves as a powerful tool for researchers in fields such as cell biology, cytology, biochemistry, proteomics, and anesthesiology. It offers a glimpse into the fascinating world of molecular structures and their impact on human physiology. Ramon Andrade from 3DCIENCIA/SCIENCE PHOTO LIBRARY has masterfully captured this scientific marvel through his skillful rendering of electron density and ribbon structures. This print is an invaluable addition to any collection exploring medical advancements and breakthroughs in understanding how anesthesia works at a molecular level.

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