Anaesthetic inhibiting an ion channel C015 / 6723
Wall Art and Photo Gifts from Science Photo Library
Anaesthetic inhibiting an ion channel C015 / 6723
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres) bound to a pentameric ligand-gated ion channel (pLGIC, blue ribbons). Propofol is used for inducing and maintaining general anaesthesia. pLGICs are targeted by general anaesthetics such as propofol which bind to the extracellular interface between the channels five monomers (subunits) and inhibit its action
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9214631
© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY
Anaesthesiology Anaesthetic Analgesia Anesthesia Anesthetic Binding Bound Cell Biology Channel Complex Complexed Cytological Cytology Drug Electron Density General Anaesthesia Inhibiting Inhibition Interacting Interaction Ion Channel Lgic Lgics Ligand Gated Ion Channel Molecules Nmda Receptor Antagonist Pentameric Ligand Gated Ion Channel Pharmacological Pharmacology Plgic Plgics Proteins Proteomics Quaternary Structure Receptor Receptors Ribbon Structure Secondary Structure System Biochemical Biochemistry Cutouts Molecular Model Molecular Structure Protein
EDITORS COMMENTS
This print showcases the intricate structure of propofol anaesthetic drug molecules bound to a pentameric ligand-gated ion channel (pLGIC). The computer-generated model, set against a clean white background, highlights the complex biochemical interaction between these two entities. Propofol is widely used in medical practice for inducing and maintaining general anesthesia, making it an essential component in surgical procedures. The blue ribbons represent the pLGIC, which serves as the target for general anesthetics like propofol. By binding to the extracellular interface between the channel's five monomers or subunits, propofol inhibits its action effectively. This molecular interaction plays a crucial role in blocking nerve signals and inducing unconsciousness during surgery. The detailed illustration not only emphasizes the significance of this chemical complex but also provides insights into cell biology and cytology. It offers viewers a glimpse into the world of pharmacology and molecular models by showcasing how specific drugs interact with proteins at a microscopic level. Ramon Andrade from 3DCIENCIA/SCIENCE PHOTO LIBRARY has masterfully captured this artwork that combines science and artistry seamlessly. This image represents cutting-edge research in biochemistry and proteomics while simultaneously appealing to those interested in visual aesthetics. It serves as a reminder of how scientific advancements continue to shape our understanding of medicine and anesthesia, ultimately improving patient care worldwide.
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