Antibiotic resistance enzyme molecule C017 / 2272
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Antibiotic resistance enzyme molecule C017 / 2272
Antibiotic resistance enzyme. Molecular model of the New Delhi metallo-beta-lactamase 1 enzyme. This bacterial enzyme confers antibiotic resistance on cells that carry it. The gene that codes for the enzyme is found on a plasmid, a ring of DNA that is separate to the cells main DNA, and so can be transferred between cells in close contact. This is possible even if the bacteria do not belong to the same genus. The enzyme inactivates antibiotics in the beta-lactam group, including penicillin and carbapenems, which are the last line of defence used against other drug-resistant bacteria
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9341803
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Antibiotic Resistance Antibiotic Resistant Bacterial Enzyme Microbiology Ndm 1 New Delhi Metallo Beta Lactamase 1 Secondary Structure Superbug Biochemical Biochemistry Cutouts Microbiological Molecular Molecular Model
EDITORS COMMENTS
This print showcases the intricate molecular structure of Antibiotic resistance enzyme C017 / 2272, also known as New Delhi metallo-beta-lactamase 1 (NDM-1). The image depicts a detailed illustration of this bacterial enzyme, which plays a significant role in conferring antibiotic resistance on cells that harbor it. The gene responsible for encoding this enzyme is found on a plasmid, a separate ring of DNA from the cell's main genetic material. This unique characteristic allows for the transfer of the gene between cells in close proximity, even if they do not belong to the same genus. Such horizontal gene transfer contributes to the rapid spread and emergence of antibiotic-resistant bacteria. The NDM-1 enzyme effectively neutralizes antibiotics belonging to the beta-lactam group, including penicillin and carbapenems – our last line of defense against other drug-resistant bacteria. Its ability to render these vital drugs ineffective poses an alarming threat in combating infectious diseases. Displayed against a white background, this artwork emphasizes both its scientific significance and aesthetic appeal. The intricate protein fold and zinc ion within the molecule are highlighted with precision, providing valuable insights into its structure and function. This visually striking image serves as a reminder of the urgent need for continued research and development efforts to combat antibiotic resistance—a global health crisis that demands immediate attention from scientists, healthcare professionals, policymakers, and society at large.
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