Beta secretase inhibitor, molecular model
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Beta secretase inhibitor, molecular model
Beta secretase inhibitor, molecular model. The inhibitor molecule (centre, also shown in C015/1977) is bound to the beta secretase enzyme (partially seen). This enzyme, of the type known as aspartic-acid protease, is also known as beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It is a transmembrane protein that is thought to play a role in Alzheimers disease through the build up of amyloid plaques in the brain. Drugs that inhibit this enzyme may help slow the progress of the disease
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9214805
© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY
Amyloid Amyloid Plaques Asp2 Aspartyl Protease 2 Bace Bace1 Beta Secretase Beta Site Beta Site App Cleaving Enzyme 1 Binding Biomolecule Complex Drug Enzyme Graphic Inhibiting Inhibitor Interacting Macromolecule Memapsin Memapsin 2 Membrane Associated Aspartic Protease Molecular Biology Proteomics Ribbons Secondary Structure Transmembrane Protein Biochemistry Molecular Model Neurological Neurology Protein
EDITORS COMMENTS
This print showcases a molecular model of a Beta secretase inhibitor, shedding light on the intricate world of drug development and its potential impact on Alzheimer's disease. The inhibitor molecule takes center stage in this artwork, elegantly bound to the beta secretase enzyme, which is only partially visible. This particular enzyme belongs to the aspartic-acid protease family and goes by various names such as BACE-1 or beta-site amyloid precursor protein cleaving enzyme 1. The significance of this molecular interaction lies in its association with Alzheimer's disease, where the build-up of amyloid plaques in the brain plays a crucial role. Scientists believe that drugs inhibiting this specific enzyme can potentially slow down the progression of this devastating neurodegenerative disorder. Against a pristine white background, this graphic representation beautifully captures the complexity and interplay between molecules within our bodies. It serves as a visual testament to advancements made in medical research and highlights how understanding these intricate structures at a molecular level can pave the way for innovative therapeutic interventions. Created by 3dciencia and curated by Ramón Andrade from Science Photo Library, this artwork combines elements from biochemistry, neurology, and molecular biology into an aesthetically pleasing composition. It symbolizes hope for those affected by Alzheimer's disease while emphasizing the importance of ongoing scientific exploration in finding effective treatments for neurological disorders.
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