Ketamine drug binding to ion channel
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Ketamine drug binding to ion channel
Ketamine drug binding to ion channel, molecular model. Several molecules of the drug ketamine binding to a pentameric ligand-gated ion channel (pLGIC). Ketamine is used for inducing and maintaining general anaesthesia. The ketamine molecules are the smaller units (including colour-coded spherical atoms) binding to the large receptor protein forming the shape of a channel (centre). The anaesthetic molecules bind to the extracellular interface between the receptors five monomers. There are five ketamine molecules per receptor. This model shows the receptors structure as an electron density map
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9241551
© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY
Anaesthetic Analgesia Anesthesia Anesthetic Anti Depressants Awareness Binding Bipolar Disorder Bronchodilation Bronchospasm Channel Depression Drug Electron Density General Anaesthesia General Anesthesia Graphic Hallucinations Interaction Ion Channel Ketalar Ketamine Ketanest Ketaset Lgic Lgics Ligand Gated Ion Channel Nervous Neuron Nnmda Receptor Antagonist Pentameric Ligand Gated Ion Channel Pharmacological Pharmacology Plgic Plgics Receptor System Treatment Biochemical Biochemistry Cutouts Molecular Model Molecular Structure Protein
EDITORS COMMENTS
This print from Science Photo Library showcases the intricate molecular interaction between the drug ketamine and an ion channel. The image depicts a pentameric ligand-gated ion channel (pLGIC) in the center, with several molecules of ketamine binding to it. Ketamine is widely used for inducing and maintaining general anesthesia. The smaller units of ketamine, represented by color-coded spherical atoms, elegantly bind to the large receptor protein forming the shape of a channel. Specifically, these anaesthetic molecules attach themselves to the extracellular interface between the five monomers of the receptor. Each receptor accommodates five ketamine molecules. The electron density map beautifully illustrates this complex biochemical interaction within our nervous system. This artwork provides valuable insights into pharmacology and medical research related to analgesia, bronchodilation, and even psychiatric conditions like bipolar disorder. The white background enhances focus on this remarkable scientific illustration that combines elements of chemistry, biochemistry, and medicine. It serves as a visual reminder of how drugs interact at a molecular level within our bodies. It is important to note that this print does not represent any commercial use or endorsement but rather offers an educational perspective on the fascinating world of molecular structures and their impact on human health.
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