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T-cell receptor - MHC complex

T-cell receptor - MHC complex


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T-cell receptor - MHC complex

T-cell receptor - MHC complex. Computer model showing the molecular structure of a T-cell receptor (TCR, pink and blue) bound to an allogeneic (non-self) major histocompatibility complex (MHC) molecule (purple, grey and green). TCRs are found on the surface of T-cells, a type of white blood cell (lymphocyte). T-cells are part of the bodys immune response. Engagement of the TCR with an antigen results in activation of its T-cell through a series of biochemical events, mediated by associated enzymes, co-receptors, and specialized accessory molecules. MHCs indicate whether a cell (or cells) is from the same organism as the T-cell. If they are non-self then an immune response is triggered and the T-cell receptors are configured to recognise the MHC

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6304871

© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Antigen Heterodimer Immune Response Immune System Immunity Lymphocyte Major Histocompatibility Complex Recognition T Lymphocyte Bio Chemistry Biochemical Molecular Model Pathogen


EDITORS COMMENTS
This print showcases a computer-generated model of the T-cell receptor - MHC complex, revealing the intricate molecular structure that governs our immune system. In vibrant hues of pink, blue, purple, grey, and green, this artwork delves into the realm of biology and chemistry. The T-cell receptor (TCR), depicted in shades of pink and blue, is an essential component found on the surface of T-cells. These white blood cells play a crucial role in our body's immune response. When engaged with an antigen, represented by specialized molecules within our bodies or foreign pathogens invading it, a cascade of biochemical events occurs. The allogeneic major histocompatibility complex (MHC) molecule takes center stage in this image with its striking combination of purple, grey, and green tones. Acting as indicators for self-recognition within our organism's cells or non-self recognition when encountering foreign entities like viruses or bacteria. Through this mesmerizing illustration created by Science Photo Library's talented artists using cutting-edge technology and scientific knowledge from biochemistry to immunology; we gain insight into how these molecular interactions trigger an immune response within us. The configuration changes occurring in T-cell receptors allow them to recognize specific MHC molecules associated with antigens. This remarkable piece serves as a reminder that even at the microscopic level there exists a fascinating world where biological processes intertwine seamlessly with chemical reactions to safeguard our health against potential threats.

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