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Histone Collection

Histones are essential proteins that play a crucial role in DNA packaging and gene expression

Background imageHistone Collection: Nucleosome molecule

Nucleosome molecule, computer model. A nucleosome is a subunit of chromatin, the substance that forms chromosomes. It consists of a short length of DNA (deoxyribonucleic acid)

Background imageHistone Collection: DNA nucleosome, molecular model

DNA nucleosome, molecular model
DNA nucleosome. Molecular model of a nucleosome, the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: DNA nucleosome, molecular model F007 / 9883

DNA nucleosome, molecular model F007 / 9883
DNA nucleosome. Molecular model of a nucleosome, the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: DNA nucleosome, molecular model F007 / 9888

DNA nucleosome, molecular model F007 / 9888
DNA nucleosome. Molecular model of a nucleosome, the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: DNA nucleosome molecule

DNA nucleosome molecule
DNA nucleosome, molecular model. This is the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: Gene expression, artwork

Gene expression, artwork
Gene expression. Computer artwork showing the process of transcription, the first stage or gene expression. Here, a chromosome (distance)

Background imageHistone Collection: Sir3 gene silencer acting on DNA F006 / 9730

Sir3 gene silencer acting on DNA F006 / 9730
Sir3 gene silencer acting on DNA, molecular model. Sir3 (light blue) is acting on a circular strand of DNA (deoxyribonucleic acid, pink)

Background imageHistone Collection: DNA tetranucleosome, molecular model F006 / 9555

DNA tetranucleosome, molecular model F006 / 9555
DNA tetranucleosome. Molecular model of four nucleosomes, or a tetranucleosome. Nucleosomes are the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: Nucleosome molecule F006 / 9323

Nucleosome molecule F006 / 9323
Nucleosome, molecular model. A nucleosome is a subunit of chromatin, the substance that forms chromosomes. It consists of a short length of DNA (deoxyribonucleic acid)

Background imageHistone Collection: Nucleosome molecule F006 / 9314

Nucleosome molecule F006 / 9314
Nucleosome, molecular model. A nucleosome is a subunit of chromatin, the substance that forms chromosomes. It consists of a short length of DNA (deoxyribonucleic acid)

Background imageHistone Collection: Nucleosome molecule F006 / 9235

Nucleosome molecule F006 / 9235
Nucleosome, molecular model. A nucleosome is a subunit of chromatin, the substance that forms chromosomes. It consists of a short length of DNA (deoxyribonucleic acid)

Background imageHistone Collection: DNA packaging, artwork C016 / 7517

DNA packaging, artwork C016 / 7517
DNA packaging. Computer artwork showing how DNA (deoxyribonucleic acid) is packaged within cells. Two DNA strands, consisting of a sugar-phosphate backbone attached to nucleotide bases

Background imageHistone Collection: DNA packaging, illustration C018 / 0747

DNA packaging, illustration C018 / 0747
DNA packaging. Illustration showing how DNA (deoxyribonucleic acid) is packaged within cells. Two DNA strands, consisting of a sugar-phosphate backbone attached to nucleotide bases

Background imageHistone Collection: Nucleosome core particle bound to DNA C014 / 0872

Nucleosome core particle bound to DNA C014 / 0872
Nucleosome core particle bound to DNA. Molecular model showing a nucleosome core particle (green and purple) bound to a strand of DNA (deoxyribonucleic acid, blue and red)

Background imageHistone Collection: DNA nucleosome, molecular model C016 / 8549

DNA nucleosome, molecular model C016 / 8549
DNA nucleosome. Molecular model of a nucleosome, the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Background imageHistone Collection: Sir3 gene silencer acting on DNA C015 / 7062

Sir3 gene silencer acting on DNA C015 / 7062
Sir3 gene silencer acting on DNA, molecular model. Sir3 (purple and grey) is acting on a circular strand of DNA (deoxyribonucleic acid, red)

Background imageHistone Collection: Sir3 gene silencer acting on DNA C015 / 7061

Sir3 gene silencer acting on DNA C015 / 7061
Sir3 gene silencer acting on DNA

Background imageHistone Collection: Sir3 gene silencer acting on DNA C016 / 2325

Sir3 gene silencer acting on DNA C016 / 2325
Sir3 gene silencer acting on DNA, molecular model. Sir3 (bright green) is acting on a circular strand of DNA (deoxyribonucleic acid, red and yellow)

Background imageHistone Collection: Sir3 gene silencer acting on DNA C016 / 2324

Sir3 gene silencer acting on DNA C016 / 2324
Sir3 gene silencer acting on DNA, molecular model. Sir3 (light blue) is acting on a circular strand of DNA (deoxyribonucleic acid, pink)

Background imageHistone Collection: Unstressed cells

Unstressed cells (Image 1 of 2). Immunofluorescent light micrograph of unstressed kidney cells. The nuclei contain the RNA (ribonucleic acid)-binding protein TIA (blue) and DNA (deoxyribonucleic acid)

Background imageHistone Collection: Chromatin beads, artwork

Chromatin beads, artwork
Chromatin beads. Computer artwork of strands of DNA (deoxyribonucleic acid, purple) coiled around histone cores (red) to form the less condensed form of chromatin

Background imageHistone Collection: Chromatin fibre, artwork

Chromatin fibre, artwork
Chromatin fibre. Computer artwork of strands of DNA (deoxyribonucleic acid, green) coiled around histone cores (multicoloured) to form a chromatin fibre

Background imageHistone Collection: Mouse chromatin protein, molecular model

Mouse chromatin protein, molecular model
Mouse chromatin protein. Molecular model of the structure of chromatin proteins found in mice. This is similar, but not identical, to the same proteins found in humans

Background imageHistone Collection: Chromatin condensation, diagram

Chromatin condensation, diagram. This sequence, from right to left, shows the stages by which a long strand of DNA (deoxyribonucleic acid)

Background imageHistone Collection: Histone structures, diagram

Histone structures, diagram. Histone cores are cylindrical structures around which the genetic molecule DNA (deoxyribonucleic acid) is wound with other proteins to form chromatin

Background imageHistone Collection: Chromatin structure, diagram

Chromatin structure, diagram. The main artwork shows various molecules and a strand of DNA (deoxyribonucleic acid, red) looping round a cylindrical histone core (blue)

Background imageHistone Collection: DNA packaging, artwork

DNA packaging, artwork
DNA packaging. Computer artwork showing how DNA (deoxyribonucleic acid) is packaged within cells. Two DNA strands, consisting of a sugar-phosphate backbone attached to nucleotide bases

Background imageHistone Collection: Cellular packaging of DNA, artwork

Cellular packaging of DNA, artwork
Cellular packaging of DNA. Artwork of a strand of the genetic material DNA (deoxyribonucleic acid) unwound from the nucleus (blue) of a cell (orange, upper right)




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Histones are essential proteins that play a crucial role in DNA packaging and gene expression. These nucleosome molecules, depicted in various molecular models like F007/9883 and F007/9888, form the building blocks of chromatin structure. The DNA wraps around these histone proteins to create a compact structure known as the nucleosome core particle bound to DNA. This intricate arrangement not only protects our genetic material but also regulates access to genes for transcription factors and other regulatory elements. Through their interactions with DNA, histones influence gene expression by either promoting or inhibiting the activation of specific genes. This artwork depicting gene expression beautifully captures the dynamic nature of this process, where histones act as key players in orchestrating precise control over which genes are turned on or off within our cells. Understanding the intricate relationship between histones and DNA is vital for unraveling the complexities of genetics and unlocking potential therapeutic interventions for diseases influenced by aberrant gene regulation.