Spacefilled Collection (#4)

GNF-2 kinase inhibitor, molecular model. GNF-2 is used to help anti-cancer drugs overcome drug-resistant mutations. It is a selective allosteric BCR-ABL inhibitor that affects the tyrosine kinase

Cyclin-dependent kinase inhibitor complex. Molecular model of the inhibitor protein P27Kip1 bound to a cyclin-A-cyclin dependent kinase 2 complex

Haemagglutinin viral surface protein C015 / 9965
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

Amylase, molecular model C015 / 7141
Amylase. Molecular model of the enzyme alpha-amylase from human saliva. Amylase catalyses the breakdown of starch to sugars, and so starts the digestive process

Trypsin molecule with inhibitor C015 / 8436
Trypsin molecule. Molecular model of the digestive protease enzyme beta-trypsin (pink) complexed with an inhibitor (blue)

Beta-2 adrenergic receptor molecule C015 / 8456
Beta-2 adrenergic receptor. Molecular model of a human beta-2 adrenergic receptor bound to an antibody. Beta receptors respond to adrenalin, causing a sympathetic (fight or flight) response

RNA silencing molecule C015 / 7697
RNA silencing. Molecular model of a synthetic double stranded ribonucleic acid (RNA) molecule. RNA is the intermediate molecule between DNA (deoxyribonucleic acid) and its protein products

Amylase, molecular model C015 / 7140
Amylase. Molecular model of the enzyme alpha-amylase from human saliva. Amylase catalyses the breakdown of starch to sugars, and so starts the digestive process

Haemagglutinin viral surface protein C015 / 7124
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

Hepatocyte nuclear factor molecule C015 / 7699
Hepatocyte nuclear factor. Molecule model of the transcription factor hepatocyte nuclear factor 1alpha (HNF-1a). Transcription factors are proteins that bind to specific sequences of DNA

Haemoglobin, molecular model C015 / 8938
Haemoglobin, molecular model. This molecule transports oxygen around the body in red blood cells. It consists of four globin proteins (amino acid chains; orange, green, blue and purple)

Bacterial alcohol dehydrogenase molecule C015 / 7146
Bacterial alcohol dehydrogenase. Molecular model of an NADP-dependent alcohol dehydrogenase enzyme from the bacterium Thermoanaerobacter brockii

Haemagglutinin viral surface protein C015 / 9974
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

Hepatocyte nuclear factor molecule C015 / 7698
Hepatocyte nuclear factor. Molecule model of the transcription factor hepatocyte nuclear factor 1alpha (HNF-1a). Transcription factors are proteins that bind to specific sequences of DNA

Haemoglobin, molecular model C015 / 9391
Haemoglobin, molecular model. This is deoxyhaemoglobin, the molecule in its non-oxygen bound state. Haemoglobin transports oxygen around the body in red blood cells

Haemoglobin, molecular model C015 / 8939
Haemoglobin, molecular model. This molecule transports oxygen around the body in red blood cells. It consists of four globin proteins (amino acid chains; orange, green, blue and purple)

Insulin receptor molecule C015 / 9405
Insulin receptor, molecular model. The insulin receptor is a transmembrane protein, that is it spans the cellular membrane

Beta-2 adrenergic receptor molecule C015 / 8455
Beta-2 adrenergic receptor. Molecular model of a human beta-2 adrenergic receptor bound to an antibody. Beta receptors respond to adrenalin, causing a sympathetic (fight or flight) response

Insulin receptor molecule C015 / 9411
Insulin receptor, molecular model. The insulin receptor is a transmembrane protein, that is it spans the cellular membrane

Haemoglobin, molecular model C015 / 9392
Haemoglobin, molecular model. This is deoxyhaemoglobin, the molecule in its non-oxygen bound state. Haemoglobin transports oxygen around the body in red blood cells

Haemagglutinin viral surface protein C015 / 7123
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

RNA silencing molecule C015 / 7696
RNA silencing. Molecular model of a synthetic double stranded ribonucleic acid (RNA) molecule. RNA is the intermediate molecule between DNA (deoxyribonucleic acid) and its protein products

Trypsin molecule with inhibitor C015 / 8379
Trypsin molecule. Molecular model of the digestive protease enzyme beta-trypsin (pink) complexed with an inhibitor (blue)

Water molecules, artwork C017 / 7384
Water molecules. Computer artwork showing the molecular (top) and atomic (bottom) structure of water (H2O). Atoms are colour-coded: hydrogen (blue) and oxygen (white)

Hydrogen bonding in water, artwork C018 / 3560
Hydrogen bonding in water. Artwork showing the hydrogen bonding (yellow dotted lines) between five water molecules. There is a weak, partial negative charge on the oxygen atoms (red)

Human immune response molecule complex. Molecular model showing a human T-cell receptor and an HLA-A leukocyte (white blood cell) antigen bound to a TAX peptide from a virus

Pho4 transcription factor bound to DNA. Molecular model showing phosphate system positive regulatory protein (Pho4) (pink and green) bound to a strand of DNA (deoxyribonucleic acid)

Human immune response molecule complex C014 / 0871
Human immune response molecule complex. Molecular model showing a human T-cell receptor and an HLA-A leukocyte (white blood cell) antigen bound to a TAX peptide from a virus

Type I topoisomerase bound to DNA C014 / 0862
Type I topoisomerase bound to DNA. Molecular model showing a type I topoisomerase molecule (khaki) bound to a strand of DNA (deoxyribonucleic acid, pink and green)

Aspartyl-tRNA synthetase protein molecule C014 / 0874
Aspartyl-tRNA synthetase protein molecule. Molecular model showing the structure of the active site of aspartyl-tRNA synthetase (DARS) from yeast

Transcription factor bound to DNA C014 / 0868
Transcription factor bound to DNA. Molecular model showing a MATa1/MATalpha2 homeodomain heterodimer (green and pink) in complex with a strand of DNA (deoxyribonucleic acid, orange and blue)

Amyloid precursor protein molecule
Amyloid precursor protein. Molecular model showing the structure of the protease inhibitor domain of an amyloid precursor protein (APP)

Resveratrol molecule C014 / 2108
Resveratrol, molecular model. Resveratrol is a phytoalexin, a defence chemical produced by plants, found in grapes, peanuts, blueberries and some pines

Amyloid precursor protein molecule C014 / 0863
Amyloid precursor protein. Molecular model showing the structure of the protease inhibitor domain of an amyloid precursor protein (APP)

TATA box-binding protein complex C014 / 0879
TATA box-binding protein complex. Molecular model showing a TATA box-binding protein (TBP, lilac) complexed with a strand of DNA (deoxyribonucleic acid, green and red)

Methyladenine glycosylase bound to DNA C014 / 0877
Methyladenine glycosylase bound to DNA. Computer model showing a molecule of human DNA-3-methyladenine glycosylase (purple) in complex with DNA (deoxyribonucleic acid, green and orange)

Type I topoisomerase bound to DNA C014 / 0883
Type I topoisomerase bound to DNA. Molecular model showing a type I topoisomerase molecule (green) bound to a strand of DNA (deoxyribonucleic acid, pink and blue)

Resveratrol molecule C014 / 2109
Resveratrol, molecular model. Resveratrol is a phytoalexin, a defence chemical produced by plants, found in grapes, peanuts, blueberries and some pines

Methyladenine glycosylase bound to DNA. Computer model showing a molecule of human DNA-3-methyladenine glycosylase (purple) in complex with DNA (deoxyribonucleic acid, blue and orange)

HIV gp41 glycoprotein C014 / 0866
HIV gp41 glycoprotein. Model showing the molecular structure of the gp41 protein from the HIV (human immunodeficiency virus) glycoprotein envelope

Transcription factor complexed with DNA C014 / 0869
Transcription factor complexed with DNA. Computer model showing sterol regulatory element binding transcription factor 1 (SREBF1, horizontal) bound to a section of DNA (deoxyribonucleic acid)

Zinc finger bound to DNA C014 / 0864
Zinc finger bound to DNA. Molecular model showing a zinc finger molecule bound to a strand of DNA (deoxyribonucleic acid)

Epstein-Barr virus protein bound to DNA C014 / 0875
Epstein-Barr virus protein bound to DNA. Computer model showing a molecule of Epstein-Barr nuclear antigen 1 (EBNA1) bound to a strand of DNA (deoxyribonucleic acid)

HIV gp41 glycoprotein. Model showing the molecular structure of the gp41 protein from the HIV (human immunodeficiency virus) glycoprotein envelope

ATP synthase molecule. Molecular model showing the structure of ATP synthase (ATPase) subunit C. ATPase is an important enzyme that provides energy for cells through the synthesis of adenosine

Transcription factor complexed with DNA C014 / 0870
Transcription factor complexed with DNA. Computer model showing a max protein (green) bound to a strand of DNA (deoxyribonucleic acid, pink)

Nucleosome core particle bound to DNA C014 / 0872
Nucleosome core particle bound to DNA. Molecular model showing a nucleosome core particle (green and purple) bound to a strand of DNA (deoxyribonucleic acid, blue and red)

Chaperonin protein complex C014 / 0873
Chaperonin protein complex. Molecular model showing the structure of a GroEL/GroES/(ADP)7 chaperonin complex. Chaperonins are proteins that provide favourable conditions for the correct folding of

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"Exploring the Vastness of Spacefilled: From Molecules to Medicines" Delving into the intricate world of molecules, we encounter the Cytochrome b5 molecule C015 / 6696, a key player in electron transfer processes within cells. Unraveling the mysteries of DNA structure, we come across the Z-DNA tetramer molecule C015 / 6557, showcasing its unique left-handed helical conformation. Embarking on a psychedelic journey, we discover the Psilocybin drug molecule, known for its mind-altering effects and potential therapeutic applications. Witnessing precision at work, we examine the RNA-editing enzyme molecular model that plays a crucial role in modifying genetic information to ensure cellular functionality. Energizing our bodies from within, we explore the ATPase molecule responsible for powering various cellular processes by converting ATP into ADP and phosphate. Battling against viral invaders, we observe Rhinovirus and antibody molecular models (C015 / 7139 & C015 / 7138) engaged in an intricate dance of recognition and defense. Admiring art imitating life, we marvel at an artwork depicting DNA's elegant double helix structure (C017 / 7217), symbolizing life's blueprint encoded within our genes. Nourishing our bodies with essential building blocks, Valine molecule takes center stage as one of the amino acids vital for protein synthesis and muscle repair. Embracing metabolic pathways with Methionine molecule as our guide; this sulfur-containing amino acid is indispensable for protein synthesis and methylation reactions. Discovering Histidine's multifaceted nature - not only serving as an amino acid but also playing pivotal roles in pH regulation and metal ion coordination within proteins.