Cholesterol enzyme affected by a drug
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Cholesterol enzyme affected by a drug
Cholesterol enzyme being affected by a drug. Molecular model of the shape of the human enzyme Hmg-Coa reductase interacting (complexed) with the anti-cholesterol drug Fluvastatin (not seen). The model shows the helices and arrowed sheets representing the enzymes shape (secondary structure). The shapes of enzymes can be affected by drugs, preventing their function in the body. One of the functions of Hmg-Coa reductase is as the first enzyme in the metabolic pathway that produces cholesterol in the body. High levels of bad cholesterol can contribute to heart disease, and the Fluvastatin drug helps to prevent this by disrupting the function of this enzyme
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6274856
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Alpha Helix Beta Sheet Cardiac Cardiology Compound Drug Heart Disease Helices Pharmaceutic Pharmaceutics Pharmacological Pharmacology Secondary Structure Shape Sheets Statin Therapy Treatment Bio Chemistry Biochemical Computer Artwork Molecular Molecular Model
EDITORS COMMENTS
This print showcases the intricate world of biochemistry, capturing a moment where a cholesterol enzyme is being influenced by a powerful drug. The molecular model depicted here represents the shape of the human enzyme Hmg-Coa reductase, which plays a crucial role in producing cholesterol within our bodies. The image reveals helices and arrowed sheets that symbolize the secondary structure of this vital enzyme. However, what makes this snapshot truly fascinating is the absence of Fluvastatin, an anti-cholesterol drug that interacts with Hmg-Coa reductase to disrupt its function. By obstructing this enzyme's activity, Fluvastatin aids in preventing high levels of harmful cholesterol that can contribute to heart disease. Through computer artwork and scientific expertise, Science Photo Library has beautifully captured how drugs can impact enzymes' shapes and subsequently hinder their functionality within our bodies. This visual representation not only highlights the importance of pharmacology but also emphasizes how medical interventions like Fluvastatin play a significant role in maintaining cardiac health. Intriguingly complex yet visually stunning, this illustration serves as a reminder of the profound influence chemistry and medicine have on our well-being. It exemplifies how advancements in biochemistry allow us to comprehend and manipulate these microscopic interactions for therapeutic purposes. Science Photo Library once again delivers an awe-inspiring glimpse into the realm where science meets artistry through their remarkable molecular model photography.
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