Langerhans cell histiocytosis, micrograph
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Langerhans cell histiocytosis, micrograph
Langerhans cell histiocytosis. Light micrograph of blood cells in a case of Langerhans cell histiocytosis (LCH), also called X-type histiocytosis. Hystiocytosis is an excess number of histiocytes, cells that form an important part of the immune system, specifically the cells engaged in phagocytosis (engulfing and destroying foreign particles and pathogens). A histiocyte is at centre. The pale orange cells are red blood cells. In LCH, the histocytes move into bones, causing damage in the form of lesions. This sample was obtained by a puncture on a scapular mass
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9240277
© PR. J. BERNARD/CNRI/SCIENCE PHOTO LIBRARY
Blood Cell Biology Cellular Excess Haematological Haematology Histological Histopathological Histopathology Immune System Immunology Leucocyte Leukocyte Pathological Pathology White Blood Cell Abnormal Cells Circulation Circulatory System Condition Disorder Light Micrograph Light Microscope Unhealthy
EDITORS COMMENTS
This print showcases the intricate world of Langerhans cell histiocytosis (LCH), a rare condition that affects the immune system. In this light micrograph, we are offered a glimpse into the blood cells of an individual suffering from LCH, also known as X-type histiocytosis. The central focus of the image is a single histiocyte, which plays a crucial role in our body's defense mechanism by engulfing and destroying foreign particles and pathogens through phagocytosis. Surrounding this vital cell are pale orange red blood cells, highlighting their presence within this diseased state. LCH manifests when these histiocytes migrate to bones, causing significant damage in the form of lesions. The sample captured here was obtained through a puncture on a scapular mass, providing valuable insight into the pathology associated with this disorder. This photograph not only serves as an educational tool for medical professionals but also offers viewers an opportunity to appreciate the complexity and fragility of our own bodies. It reminds us that even at microscopic levels, diseases can wreak havoc on our health. Through its detailed depiction of cellular abnormalities and its connection to various fields such as biology, medicine, haematology, and immunology; this image stands as a testament to both scientific exploration and human resilience in combating disorders like Langerhans cell histiocytosis.
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