Biochemical Collection (#85)

Amlodipine high blood pressure drug, molecular model. This drug, marketed as Istin, is used to treat hypertension (high blood pressure) and angina pectoris (heart pain)

Flumazenil benzodiazepine antidote
Flumazenil benzodiazepine antagonist drug, molecular model. This drug, marketed as Anexate, is used to treat overdoses of benzodiazepine drugs, a class of sedatives that includes valium

Buspirone anti-anxiety drug molecule
Buspirone anti-anxiety drug. Computer model of a molecule of buspirone, marketed as Buspar, an anxiolytic (anti-anxiety) drug

HIV antibody therapy. Molecular model of the interaction of the HIV surface protein gp120 (green, lower right) as it interacts with a human white blood cell surface protein (CD4, blue)

Cholesterol enzyme affected by a drug
Cholesterol enzyme being affected by a drug. Molecular model of the shape of the human enzyme Hmg-Coa reductase interacting (complexed) with the anti-cholesterol drug Fluvastatin (not seen)

Amprenavir drug molecule
Amprenavir. Computer model of a molecule of the drug amprenavir. It is also known as VX-478, and is sold under the brand name Agenerase

Theobromine drug molecule
Theobromine. Computer model of a molecule of the alkaloid drug theobromine. This substance is most often consumed in products of the cacao tree, such as chocolate and cocoa

Quinapril drug molecule
Quinapril. Computer model of a molecule of the drug quinapril. It is sold under the brand name Accupril. It is an ACE (angiotensin converting enzyme) inhibitor drug

HIV enzyme being affected by a drug. Molecular model of HIVs reverse transcriptase enzyme as it interacts with a drug (not seen)

Nitroglycerin drug molecule
Nitroglycerin. Computer model of a molecule of the drug nitroglycerine. It is also known as nitroglycerin, trinitroglycerin and glyceryl trinitrate

Ampalex drug molecule
Ampalex. Computer model of a molecule of the drug made under the brand name Ampalex. It is also known by its trial name of CX-516. It is an ampakine drug, used to treat Alzheimers disease

Tacrine drug molecule
Tacrine. Computer model of a molecule of the drug tacrine. It is sold under the brand name Cognex. It is an acetylcholinesterase inhibitor drug

Cephalexin drug molecule
Cephalexin. Computer model of a molecule of the drug cephalexin. It is sold under the brand name Keflex. It is a cephalosporin antibiotic drug, used to treat bacterial infections

Atorvastatin drug molecule
Atorvastatin. Computer model of a molecule of the drug atorvastatin. It is sold under the brand name Lipitor. It is a statin drug

Azithromycin drug molecule
Azithromycin. Computer model of a molecule of the drug azithromycin. It is sold under the brand names Zithromax (Zmax) and Sumamed

Atenolol drug molecule
Atenolol. Computer model of a molecule of the drug atenolol. It is sold under the brand name Tenormin. It is a beta blocker drug, used to treat hypertension (high blood pressure)

Methamphetamine molecule. Computer graphic of the drug methamphetamine (formula C10.H15.N), a quicker acting and longer lasting derivative of amphetamine

Mescaline molecule. Computer graphic of the drug mescaline (formula C11.H17.N.O3). The atoms (tubes) are colour-coded: carbon (yellow), oxygen (red), nitrogen (blue) and hydrogen (white)

Ephedrine molecule
Ephedrine. Computer graphic of a molecule of the drug ephedrine (C10.H15.N.O). The atoms (tubes) of the molecule are colour-coded: hydrogen (white), carbon (yellow), oxygen (red) and nitrogen (blue)

Morphine molecule
Morphine. Computer model of a molecule of morphine (C17.H19.N.O3). The atoms (tubes) of this drug are colour-coded: carbon (purple), oxygen (red), hydrogen (grey) and nitrogen (yellow)

Hydrocodone drug. Molecular model of the analgesic drug hydrocodone (C18H21NO3). Atoms (sticks) are colour-coded: carbon (yellow), hydrogen (white), nitrogen (blue) and oxygen (red)

Cortisol hormone molecule. Computer model of a molecule of the steroid hormone cortisol. Atoms are represented as blobs and are colour-coded: carbon (green), hydrogen (blue) and oxygen (red)

Follicle stimulating hormone molecule. Computer artwork showing the secondary structure of a molecule of follicle stimulating hormone (FSH, bottom) and its receptor (FSHR, top)

Corticosterone hormone molecule, computer model. Atoms are represented as spheres and are colour- coded: carbon (pink), hydrogen (white) and oxygen (blue)

Erythropoietin molecule bound to receptors. Computer model of a molecule of erythropoietin (EPO) (orange) bound to two extracellular EPO receptors (pink and purple)

Prostacyclin, molecular model. This is a hormone that acts to widen blood vessels (thus lowering blood pressure) and to prevent aggregation of platelets (preventing blood clotting)

Insulin hormone, molecular model
Insulin hormone. Molecular model of the bovine form of the hormone insulin, produced by the pancreas in mammals to aid the body in metabolising sugars

Adrenaline hormone molecule
Adrenaline. Computer model of a molecule of the hormone and neurotransmitter adrenaline. It is also known as epinephrine. Adrenaline is produced by the adrenal glands

Dopamine neurotransmitter molecule
Dopamine molecule. Computer artwork of a molecule of the neurotransmitter and neurohormone dopamine (C8.H11.N.O2). The atoms are represented as spheres and are colour-coded: carbon (black)

Dopamine molecule. Computer model of a molecule of the neurotransmitter and neurohormone dopamine. The atoms are represented as spheres and are colour-coded: carbon (red), hydrogen (white)

ZP3 glycoprotein molecule
ZP3 glycoprotein. Computer artwork of a molecule of ZP3 (zona pellucida glycoprotein 3), a sperm receptor in the external membrane (zona pellucida) of a female germ cell (egg)

Thrombin protein, secondary structure
Thrombin protein, computer model. Thrombin is a protein involved in the blood coagulation (clotting) process. It converts fibrinogen (a soluble plasma glycoprotein synthesised in the liver)

GAGA transcription factor molecule. Molecular model showing the primary (rods) and secondary (helices) structure of GAGA factor (green and blue)

Chinese scorpion toxin structure. Molecular model showing the crystal structure of toxin BmBKTtx1, produced by the Chinese scorpion (Buthus martensi Karsch)

NovoSeven clotting protein molecule
NovoSeven clotting protein, molecular model. NovoSeven is the brand name for an artificial version of the natural blood protein Factor VII, or proconvertin

Cytochrome P450 protein, molecular model. This protein plays a crucial role in metabolism in animals (including humans), fungi, plants and bacteria

Section of human apolipoprotein A-I, molecular model. This is a fragment of a high-density lipoprotein (HDL) molecule known as an apolipoprotein

Heterotrimeric G protein complex molecule. Computer model showing the secondary structure of a heterotrimeric G protein complex. Alpha-helices are red and beta sheets are yellow

Streptococcal protein G molecule
Streptococcal protein G. Computer model showing the primary (ball-and-stick) and secondary (alpha- helix, blue, and beta-sheets, purple) structures of Streptococcal protein G

Src protein domain. Computer model showing the primary (rods) and secondary (alpha helix, blue and beta sheets, purple) structures of the Src homology domain 3 (SH3)

Integration host factor and DNA. Computer model of integration host factor (IHF, centre) bound to a molecule of DNA (deoxyribonucleic acid, semi- circle). The secondary structure of IHF is shown

Haemagglutinin viral surface protein, molecular model. Haemagglutinin is found on the surface of many bacteria and viruses, notably the influenza virus

C-reactive protein, molecular models. Two molecules of the protein are seen. The protein is made up of five sub-units (monomers) arranged in a ring

Human rhinovirus capsid proteins, molecular model. These are proteins from the capsid (outer protein coat) of rhinovirus 14. Rhinoviruses are responsible for causing about 50% of common colds

Haemagglutinin from bird flu virus, molecular model. This protein, H5, is found on the surface of the bird flu virus H5N1

Cytosine molecule
Cytosine. Molecular model of the nucleobase cytosine (2-oxy-4-aminopyrimidine). This is a pyrimidine-derived nucleobase found in the genetic molecules DNA (deoxyribonucleic acid)

Vitamin B2, molecular models. Vitamin B2, also called riboflavin, is an essential nutrient that humans are unable to produce and so need to obtain from their diet

Vitamin C, molecular models. Vitamin C, also called ascorbic acid, is an essential vitamin that is found in fruit and green vegetables

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