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Dendritic cell, SEM C016 / 4763

Dendritic cell, SEM C016  /  4763


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Dendritic cell, SEM C016 / 4763

Dendritic cell. Coloured ion-abrasion scanning electron micrograph (IA-SEM) showing sheet-like cellular extensions on a dendritic cell. These extensions trap HIV (human immunodeficiency virus) particles, aiding their spread through the body. Dendritic cells are a component of the bodys immune system. They are antigen-presenting cells (APCs), that is, they present pathogens or foreign molecules (antigens) to other cells of the immune system to be eliminated. HIV uses the bodys defences against itself. When dendritic cells interact with T cells, HIV is transmitted to the T cells, infecting them. IA-SEM allows nanoscale three dimensional imaging of whole cells

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9205419

© SRIRAM SUBRAMANIAM/NATIONAL INSTITUTES OF HEALTH/SCIENCE PHOTO LIBRARY

Dendritic Cell Immune Cell Immunity Immunological Immunology Surface Three Dimensional White Blood Cell Cutouts


EDITORS COMMENTS
This print showcases the intricate structure of a dendritic cell, captured using ion-abrasion scanning electron microscopy (IA-SEM). The vibrant colors against a black background highlight the sheet-like cellular extensions that adorn this immune system component. These extensions play a crucial role in trapping HIV particles, aiding their spread throughout the body. Dendritic cells are antigen-presenting cells (APCs), responsible for presenting pathogens or foreign molecules to other immune cells for elimination. However, HIV cunningly exploits these defense mechanisms by transmitting itself to T cells when interacting with dendritic cells. This viral transmission is depicted in stunning detail through nanoscale three-dimensional imaging made possible by IA-SEM technology. The white blood cell's surface appears almost sculpted as it engages in its immunological duties. This image serves as a powerful reminder of how viruses can manipulate our own immunity against us. The scientific significance of this photograph lies not only in its aesthetic appeal but also in its contribution to understanding the complex cellular processes involved in HIV transmission. Captured by Sriram Subramaniam and available from Science Photo Library, this print offers an intriguing glimpse into the microscopic world of biology and immunology. It serves as a testament to the advancements made possible through cutting-edge technologies like SEM and provides valuable insights into combating infectious diseases such as HIV/AIDS.

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